High Power HighEfficient Ultrasonic Homogenizer For Bacterial Lysis

Ultrasonic homogenizers are powerful tools to mix and homogenize solid-liquid and liquid-liquid suspensions. Ultrasonic homogenization is a mechanical process to reduce particles in a liquid so that they become uniformly small and evenly distributed. SP TECH provides powerful ultrasonic homogenizers for application in lab and industry production scale.

Bacterial cell lysis is a crucial unit operation in biomolecular analysis. Ultrasonic treatment is an efficient method that can be used to break up cells, bacteria, spores and small pieces of tissue. The mechanical energy created from an ultrasonic homogenizer’s probe creates microscopic vapor bubbles that briefly form and then collapse. This results in shock waves traveling through the sample, ultimately breaking the cell apart. To avoid overheating, the ultrasonic treatment is applied in multiple short intervals to a sample that is kept in an ice bath. It is worth noting that this method of bacterial lysis is most effective for small volumes of liquid (less than 100 mL).

Ultrasonic homogenizer in Nano materials field attracted the attention of scientists, researchers and engineers of almost any branches as nano-sized particles show unique characteristics. Their physical properties such as optical and magnetic properties, specific heats, melting points, and surface reactivity offer high potentials for material with extraordinary strengths. But the smaller particles, the more difficult becomes treatment. Ultrasonic homogenizer is often the best method to effect nano particles effectively.  Mostly, high power ultrasonic homogenizers are the only efficient way to achieve the desired milling and dispersing results of nano particles such as nanotubes, graphene, metal oxides etc.

The impact of sonication on biological and microbiological systems are manifold: Dispersing & Homogenizing, cell and tissue lysis (e.g. bacteria, yeast, viruses, algae…) & extraction of intracellular materials such as proteins, ribosomes, RNA, lipids, peptides…, plant cell transformation.