Views: 0 Author: Site Editor Publish Time: 2022-06-01 Origin: Site
Sonication uses sound waves to agitate particles in solution. It converts electrical signals into physical vibrations to break down matter. These disruptions can mix solutions, accelerate the dissolution of solids into liquids, such as sugar into water, and remove dissolved gases from liquids. In DNA testing, ultrasound breaks down molecules and destroys cells, releasing proteins for testing.Sound is a wave of alternating high and low pressures. The frequency of a sound wave is the frequency at which the particles of matter vibrate as the sound wave passes through. Sonication typically uses ultrasound at a frequency of 20 kHz (20,000 times per second) or higher. These frequencies are higher than you can hear, but it is still recommended to protect your ears during sonication, as the process can produce loud, harsh noises. The higher the frequency, the stronger the agitation of the particles. A sonicator is a powerful laboratory device with an ultrasonic generator that generates a signal to power a transducer. Transducers convert electrical signals using piezoelectric crystals - crystals that respond directly to electricity by producing mechanical vibrations. The sonicator retains and amplifies the vibration until it is delivered to the probe. The probe moves in time with the vibration, delivering it into the solution and moving up and down quickly. The sonicator operator can control the amplitude according to the properties of the solution. A small probe tip produces a stronger response than a large probe tip, but more solution is accessible to the large tip.
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